I can, and I can even use an analog stick or gyro as mouse replacement (it doesn't work without a mouse, right?) - but that's not proper gamepad support and it will be tedious when playing.
As I'm a couch gamer (and lazy), I'm still hoping for gamepad support.
Well, the full screen setting doesn't work properly and it doesn't have gamepad support. Of course you can basically run anything on a Steam Deck, but you won't have fun with everything